Labyrinth time...
Level 18 - all points in the defense tree
Just before the end of Act 1 and the fight with Megalesios, i reach what is considered to be the best farming spot for the Stonebinder's Cuffs. See where my character is on the map? This is the last rebirth fountain in Act 1. Going forward leads to Megalesios, while the 4 green X's mark the rooms where the gorgons should spawn. It's a short 20-30 second farming run. However, i got only skeleton spawns, so i had to exit the game all the way to desktop and restart, to reset the seed and get the gorgon spawns. On average i get between 4 and 8 Geomancers and Profaners per run, so unless i'm extremely unlucky, the Cuffs should drop within the next 20-30 minutes.
If i complete the act now and leave for act 2, i will lose this rebirth fountain and won't be able to farm Megalesios for the Shroud of Eternal Night or to hunt for the Stonebinder's Cuffs. The only way i can go back here, would be to take the waypoint portal back to Herakleion, but then i have to go all the way through Herakleion Highlands, Knossos Palace and the Minoan Labyrinth - that's a long walk. So i need to do my farming right now!