I used to play classic and we would would glitch our chaos runs by having a character that had killed D make game, then a character that "cannot complete quest in this game" would kill D and you wod get significanrly better drops. ..

Just wondering if that type of thing makes a difference on Baal in expansion?

Yes, you should glitch Baal as well.

it works with every quest bosses

In theory yes.

https://forums.d2jsp.org/topic.php?t=71142281