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#9731
Jan 11 2022 05:16pm
Quote (Goomshill @ Jan 11 2022 05:13pm)
If it happened anywhere, at random, it would appear first in a city. Sure. Would it appear first in a city that just so happens to be hosting gain of function research of adding that exact same furin cleavage site to coronaviruses?
Its 'circumstantial evidence' in the same sense that finding a killer's DNA and bloody fingerprints at the murder scene is still 'circumstantial'. They aren't direct evidence, they could be explained away by incredibly unlikely null hypotheses. It still requires inference, reasoning and allows the construction of denials however improbable they may be. Maybe the murderer says his car broke down in front of the woman's house, she invited him inside her house and then inside her cunt and then he left as two puerto rican guys walked in. Just an incredibly unlikely coincidence.

There are over 10,000 cities on earth, not including small towns. Lyme disease is named after the town of 2,352 people. And it just so happens that Covid-19 had its first major outbreak at a crime scene with the CCP's bloody fingerprints all over it. And they blamed two puerto rican guys.


If they were intentionally adding a furin cleavage site to coronavirus has it would be insanely apparent on first inspection of the genome. You can't just add things to a genome without leaving any traces. It would be incredibly obvious that it had been intentionally modified and no such evidence exists
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#9732
Jan 11 2022 05:20pm
Quote (NetflixAdaptationWidow @ Jan 11 2022 05:11pm)
Yes, we've got basically the entire family tree constructed this point except for whatever the immediate step was before human infection. There are loads of candidates for predecessor viruses and it really doesn't matter which one it was.

We can be incredibly confident it was not any kind of game of function experiment gone wrong. There are no signs of that kind of modification in the virus genome. The absolute best you could get is that it was created through serial passage with some other animal but even that is pretty suspect and wouldn't be differentiable from a wild virus

If you've got a big project with dozens and dozens of animals undergoing cereal passage that's kind of hard to keep a secret


No we can't.
We can be confident it wasn't created by genetic splicing using public methods like crispr, but we cannot say it wasn't the result of studies on recombining viruses through exposure experiments to study gain of function, especially those trying to recombine coronaviruses to get that very specific furin cleavage site, which is precisely what the WIV was engaged in. As the top health officials from various countries and agencies said in that email chain with Fauci, the odds of the virus naturally recombining to have that specific set of mutations without any other changes that would neutralize it, was astronomical. Especially when no coronavirus sample in the wild has ever shown any related mutation. Its like if you take a dozen decks of shuffled cards and throw them into the air and they land with 12 x 47 cards face-down and a 12x royal flushes all face-up;

Quote
I really can’t think of a plausible
natural scenario where you get from the bat virus or one very similar
to it to nCoV where you insert exactly 4 amino acids 12 nucleotide
that all have to be added at the exact same time to gain this function
– that and you don’t change any other amino acid in S2? I just can’t
figure out how this gets accomplished in nature


If natural coronaviruses were evolving this trait in the wild, you'd expect to find a spectrum of samples with near-miss mutations, and especially with all kinds of unrelated noise in their DNA from all the mutations inbetween.
If the coronavirus was inheriting this trait from recombining with another virus with that exact furin cleavage site that it was being intentionally exposed to by researchers, it would look just like Covid-19, funny that.
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#9733
Jan 11 2022 05:21pm
Quote (NetflixAdaptationWidow @ 12 Jan 2022 00:11)
Yes, we've got basically the entire family tree constructed this point except for whatever the immediate step was before human infection. There are loads of candidates for predecessor viruses and it really doesn't matter which one it was.

We can be incredibly confident it was not any kind of game of function experiment gone wrong. There are no signs of that kind of modification in the virus genome. The absolute best you could get is that it was created through serial passage with some other animal but even that is pretty suspect and wouldn't be differentiable from a wild virus

If you've got a big project with dozens and dozens of animals undergoing cereal passage that's kind of hard to keep a secret


I'm willing to believe you, but I don't really understand that, so please help me out: Say the Chinese took a wild sample from some bats, then tried to play around with the furin cleavage FoR tHe ScIeNcE, this happens to increase transmissibility and allow the virus to jump to humans, a lab staffer breaks protocol and lets this marginally modified virus escape to the city (Wuhan) - why is that not a possibility? I'm not an expert in biology, virology or genetics, so I gotta wonder: how exactly could we tell apart such a man-made modification from natural evolution?

This post was edited by Black XistenZ on Jan 11 2022 05:24pm
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#9734
Jan 11 2022 05:21pm
Quote (Goomshill @ Jan 11 2022 06:13pm)
If it happened anywhere, at random, it would appear first in a city. Sure. Would it appear first in a city that just so happens to be hosting gain of function research of adding that exact same furin cleavage site to coronaviruses?
Its 'circumstantial evidence' in the same sense that finding a killer's DNA and bloody fingerprints at the murder scene is still 'circumstantial'. They aren't direct evidence, they could be explained away by incredibly unlikely null hypotheses. It still requires inference, reasoning and allows the construction of denials however improbable they may be. Maybe the murderer says his car broke down in front of the woman's house, she invited him inside her house and then inside her cunt and then he left as two puerto rican guys walked in. Just an incredibly unlikely coincidence.

There are over 10,000 cities on earth, not including small towns. Lyme disease is named after the town of 2,352 people. And it just so happens that Covid-19 had its first major outbreak at a crime scene with the CCP's bloody fingerprints all over it. And they blamed two puerto rican guys.


If COVID leaked from a private pharmaceutical company, the easiest coverup would be blaming China and pulling on their strings within the "paid speaker" "Doctor" arena and within the media.

There are over 20,000 Biosafety level 2 or higher laboratories in the world.

Plus the original COVID broadcasts were all bullshit. None of them listed the names of doctors, locations, or gave traceable studies providing evidence.
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#9735
Jan 11 2022 05:23pm
Quote (Black XistenZ @ Jan 11 2022 05:21pm)
I'm willing to believe you, but I don't really understand that, so please help me out: Say, the Chinese took a wild sample from some bats, then tried to play around with the furin cleavage FoR tHe ScIeNcE, this happens to increase transmissibility and allow the virus to jump to humans, a lab staffer breaks protocol and lets this marginally modified virus escape to the city (Wuhan) - why is that not a possibility? I'm not an expert in biology, virology or genetics, so I gotta wonder: how exactly could we tell apart such a man-made modification from natural evolution?


You would use an enzyme that cleaves DNA at certain sequences. And you would be able to identify multiple and the exact site that was cleaved and recombined. These sequences are really well established. So they also would have had to make a whole set of entirely new restriction endonuclease that uses a novel sequence never published before instead of using a cheap well characterized ones off the shelf.

This post was edited by NetflixAdaptationWidow on Jan 11 2022 05:24pm
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#9736
Jan 11 2022 05:25pm
Quote (NetflixAdaptationWidow @ Jan 11 2022 03:23pm)
You would use an enzyme that cleaves DNA at certain sequences. And you would be able to identify multiple and the exact site that was cleaved and recombined. These sequences are really well established. So they also would have had to make an entirely new restriction endonuclease that uses a novel sequence never published before instead of using a cheap well characterized one off the shelf.


Nah you can gibson and skip the enzymes. The furin site is objectively odd but doesn't mean it had to come from a lab.
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#9737
Jan 11 2022 05:25pm
Quote (Sioux @ Jan 11 2022 05:15pm)
There's no evidence they were doing gain of function research on furin cleavage. The viral institute was founded in a region with a high circulating population of coronaviruses in the wild to study.


You shush with your easily searchable facts
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#9738
Jan 11 2022 05:28pm
Quote (NetflixAdaptationWidow @ Jan 11 2022 05:34pm)
The lab you're referencing was several km from the wet market. The Wuhan CDC building that's right next to the wet market isn't a laboratory.

So... there's no reason to assume the wet market thing was a cover up. They had nothing to cover up by linking it to the wet market.



At best you have minor circumstantial evidence.


Several km? Lol
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#9739
Jan 11 2022 05:31pm
Quote (thesnipa @ Jan 11 2022 05:28pm)
Several km? Lol


I forget the number. A km. Doesnt really matter.
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#9740
Jan 11 2022 05:33pm
Quote (Goomshill @ Jan 11 2022 03:20pm)
No we can't.
We can be confident it wasn't created by genetic splicing using public methods like crispr, but we cannot say it wasn't the result of studies on recombining viruses through exposure experiments to study gain of function, especially those trying to recombine coronaviruses to get that very specific furin cleavage site, which is precisely what the WIV was engaged in. As the top health officials from various countries and agencies said in that email chain with Fauci, the odds of the virus naturally recombining to have that specific set of mutations without any other changes that would neutralize it, was astronomical. Especially when no coronavirus sample in the wild has ever shown any related mutation. Its like if you take a dozen decks of shuffled cards and throw them into the air and they land with 12 x 47 cards face-down and a 12x royal flushes all face-up;



If natural coronaviruses were evolving this trait in the wild, you'd expect to find a spectrum of samples with near-miss mutations, and especially with all kinds of unrelated noise in their DNA from all the mutations inbetween.
If the coronavirus was inheriting this trait from recombining with another virus with that exact furin cleavage site that it was being intentionally exposed to by researchers, it would look just like Covid-19, funny that.


https://www.sciencedirect.com/science/article/pii/S1873506120304165

Its happened many times that we're aware of
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