Quote (Black XistenZ @ Aug 14 2021 09:17pm)
Afaik, exactly that is the original idea behind the mRNA vaccines: stimulate an immune response against specific cancer cells to enable the immune system to fight them off on its own, rather than flooding the system with toxins (chemotherapy) or injecting antibodies which were grown outside of the patients body.
Some cancers are a result of one or many mutant genes. For instance, Synovial Sarcoma is a result of a specific fusion of two genes resulting in a protein that is basically a combination of two proteins, and that activates growth pathways all the time. This protein is a new fusion that isn't anywhere else in the body, so we could theoretically create an mRNA sequence to the fusion area of the protein and train the body to target it. This probably won't work for cancers that have promoters mutated instead of protein mutations, but nothing is ever going to work on all cancers with how diverse of a disease cancer is.
Quote (theCrossbones @ Aug 14 2021 09:34pm)
Yes seems similar to some of the immune system recognition they have done with cold virus/HIV virus stuff.
Seems like it should work. Lol wishful thinking I’m sure
The reason your body doesn't build immunity to vaccines is because immune cells are the targets. If a T-Cell tries to grab a virus and chop it up to show to your B cells, it gets infected. So it fundamentally disrupts the pathway that allows us to recognize viruses.
The mRNA technology could solve this, but it's tricky to avoid the same systems that the HIV virus compromises. mRNA might work, if we're lucky.