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Jul 13 2021 03:46pm
Quote (NetflixAdaptationWidow @ Jul 13 2021 02:41pm)
I absolutely love the doulbethink of all the conspiratards.

The virus isn't deadly at all, but Cuomo is a monster for sending infected people back to nursing homes.

Trump is the lord and savior who brought us the vaccine in record time but it's also a dangerous plot to microchip us and causes massive side effects.

The CDC admits vaccines are dangerous by issuing warnings, but they're also hiding all the side effects and not allowing anybody to ask questions about safety.

The list goes on and on. Every anti-vaxxer and conspiracy theorist falls for at least a few.


"I absolutely love the doulbethink of all the conspiratards."
(things be swirling around in your head dont equate into facts. what you think people think is your own delusions.)
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Jul 13 2021 03:47pm
Was curious if there was any information on spike protein mutations in delta and how they might affect antibody response. This was the first paper I came across.

https://www.nature.com/articles/s41586-021-03777-9

Quote
The SARS-CoV-2 B.1.617 lineage was identified in October 2020 in India1–5. It has since then become dominant in some indian regions and UK and further spread to many countries6. The lineage includes three main subtypes (B1.617.1, B.1.617.2 and B.1.617.3), harbouring diverse Spike mutations in the N-terminal domain (NTD) and the receptor binding domain (RBD) which may increase their immune evasion potential. B.1.617.2, also termed variant Delta, is believed to spread faster than other variants. Here, we isolated an infectious Delta strain from a traveller returning from India. We examined its sensitivity to monoclonal antibodies (mAbs) and to antibodies present in sera from COVID-19 convalescent individuals or vaccine recipients, in comparison to other viral strains. Variant Delta was resistant to neutralization by some anti-NTD and anti-RBD mAbs including Bamlanivimab, which were impaired in binding to the Spike. Sera from convalescent patients collected up to 12 months post symptoms were 4 fold less potent against variant Delta, relative to variant Alpha (B.1.1.7). Sera from individuals having received one dose of Pfizer or AstraZeneca vaccines barely inhibited variant Delta. Administration of two doses generated a neutralizing response in 95% of individuals, with titers 3 to 5 fold lower against Delta than Alpha. Thus, variant Delta spread is associated with an escape to antibodies targeting non-RBD and RBD Spike epitopes.




In other words, it's almost certainly escaping immunity via spike protein mutations. This is.... not great. We just have to hope that as it mutates it also reduces symptoms. On the long run viruses tend to become more infectious and less deadly, so hopefully this one heads down that path sooner rather than later.

This post was edited by NetflixAdaptationWidow on Jul 13 2021 03:48pm
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Jul 13 2021 03:57pm
Quote (NetflixAdaptationWidow @ Jul 13 2021 02:47pm)
Was curious if there was any information on spike protein mutations in delta and how they might affect antibody response. This was the first paper I came across.

https://www.nature.com/articles/s41586-021-03777-9





In other words, it's almost certainly escaping immunity via spike protein mutations. This is.... not great. We just have to hope that as it mutates it also reduces symptoms. On the long run viruses tend to become more infectious and less deadly, so hopefully this one heads down that path sooner rather than later.


you have even bigger problems with whats up with the animal experiments. mRNA delivery system into the cells is a fukd up dogchit idea to begin with. ya but it a bill gates thing

" This is.... not great."
(you just might be beginning to realize some things?

This post was edited by TiStuff on Jul 13 2021 03:59pm
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Jul 13 2021 04:00pm
Quote (TiStuff @ Jul 13 2021 04:57pm)
you have even bigger problems with whats up with the animal experiments. mRNA delivery system into the cells is a fukd up dogchit idea to begin with. ya but it a bill gates thing


If you think there's something interesting in the animal experiments then post a link to the published data. Not a video about it, not a bitchute link, the published data. Because I've only seen one person link papers, and the papers he linked explicitly said the animals didn't die.

So if you have a PRIMARY source, show it.
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Jul 13 2021 04:03pm
Quote (NetflixAdaptationWidow @ Jul 13 2021 03:00pm)
If you think there's something interesting in the animal experiments then post a link to the published data. Not a video about it, not a bitchute link, the published data. Because I've only seen one person link papers, and the papers he linked explicitly said the animals didn't die.

So if you have a PRIMARY source, show it.


why dont you show it dude. mr endless excuses. what do you have ? mr assertion all the time. i have provided you with a pathway of inquiry and your being a chicken chit

This post was edited by TiStuff on Jul 13 2021 04:03pm
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Jul 13 2021 04:04pm
Quote (TiStuff @ Jul 13 2021 05:03pm)
why dont you show it dude. mr endless excuses. what do you have ? mr assertionall the time. i have provided you with a pathway of inquiry and your being a chicken chit


Because I don't know what you're referencing. I can't read your mind.
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Jul 13 2021 04:06pm
Quote (NetflixAdaptationWidow @ 13 Jul 2021 23:47)
Was curious if there was any information on spike protein mutations in delta and how they might affect antibody response. This was the first paper I came across.

https://www.nature.com/articles/s41586-021-03777-9


In other words, it's almost certainly escaping immunity via spike protein mutations. This is.... not great. We just have to hope that as it mutates it also reduces symptoms. On the long run viruses tend to become more infectious and less deadly, so hopefully this one heads down that path sooner rather than later.


There's basically two ways it could mutate without creating problems: becoming more infectious and less deadly, or developing a stronger* immune escape without simultaneously increasing transmissibility. The latter would also be okay because a more lethal strain which doesnt prevail against other, more transmissible strains is no problem. See the Beta variant which hasn't gotten traction in any region where Alpha or Delta have been circulating.

It should also be noted that fully vaccinated persons are both getting infected and spreading the virus to others are greatly reduced rates, so that each vaccination effectively reduces the R_0 of the virus. Once the vaccination campaign wraps up and we lift the remaining restrictions, there will be a short wave among the unvaccinated children and young adults who have lots of social contacts but almost never severe symptoms or hospitalization, and then the immunity rate in the population will be high enough to keep the spread of Delta at bay while the vaccinations of the risk groups keep hospitalizations sufficiently low. This balance can only be broken up by a new variant which is, at the same time, more infectious and more resistant to vaccinations than Delta. Also, the president of BioNTech has already stated that his company could adjust its vaccine to new variants in around 6 weeks.






*a full immune escape which drops the effectiveness of a complete vaccination by a huge chunk would of course be devastating, but most experts I've heard from agree that such a full immune escape is very unlikely and that we will most definitely only see partial immune escapes of varying degree.
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Jul 13 2021 04:07pm
Quote (NetflixAdaptationWidow @ Jul 13 2021 03:04pm)
Because I don't know what you're referencing. I can't read your mind.


because i am not referencing anything

i am telling you. go find out what happened to the animal studies. its a simple idea. go challenge your bias. stop making excuses about it
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Jul 13 2021 04:09pm
Quote (TiStuff @ Jul 13 2021 05:07pm)
because i am not referencing anything

i am telling you. go find out what happened to the animal studies. its a simple idea. go challenge your bias. stop making excuses about it


"the animal studies" is far too broad to be meaningful. They've been studying RNA delivery into living tissues for decades now. You're going to have to be far more specific about what you want.

Also, why would I bother looking at animal studies when we have human studies with tens of thousands of participants?

This post was edited by NetflixAdaptationWidow on Jul 13 2021 04:09pm
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Jul 13 2021 04:10pm
Quote (Black XistenZ @ Jul 13 2021 03:06pm)
There's basically two ways it could mutate without creating problems: becoming more infectious and less deadly, or developing a stronger* immune escape without simultaneously increasing transmissibility. The latter would also be okay because a more lethal strain which doesnt prevail against other, more transmissible strains is no problem. See the Beta variant which hasn't gotten traction in any region where Alpha or Delta have been circulating.

It should also be noted that fully vaccinated persons are both getting infected and spreading the virus to others are greatly reduced rates, so that each vaccination effectively reduces the R_0 of the virus. Once the vaccination campaign wraps up and we lift the remaining restrictions, there will be a short wave among the unvaccinated children and young adults who have lots of social contacts but almost never severe symptoms or hospitalization, and then the immunity rate in the population will be high enough to keep the spread of Delta at bay while the vaccinations of the risk groups keep hospitalizations sufficiently low. This balance can only be broken up by a new variant which is, at the same time, more infectious and more resistant to vaccinations than Delta. Also, the president of BioNTech has already stated that his company could adjust its vaccine to new variants in around 6 weeks.






*a full immune escape which drops the effectiveness of a complete vaccination by a huge chunk would of course be devastating, but most experts I've heard from agree that such a full immune escape is very unlikely and that we will most definitely only see partial immune escapes of varying degree.


"becoming more infectious and less deadly,"
(its already this. thats why the fearmongering is done with "cases" "cases" "cases" also for the same reason why none of you will answer the simple question "what is the claimed death count of year 2020 and provide link"

your a bunch of fukn dr fraudi larpers

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