that wasn't how it worked. as long as you went to act 2 before leaving the game, andy was quest bugged, didnt have to do anything else.
but no, andy is permanently quest bugged in d2r. there's fake news going around saying she is no longer quest bugged with the dlc, but it's not true. her drops got nerfed, but she is still perma quest bugged.
is key(A1, 2, 5) drop rate nerfed too?