Id suggest joining discord and asking

The fastest way is you should try to research information on pd2 wiki

jewel dust, used for crafting and is the same as a jewel. puzzlebox for adding sockets. corruption, you can cube it with an item to add a random modifier (middle)
some parts for opening boss portals (left side under keys)
items for rerolling maps and etc (down)
crafting stuff (right side next to gems)

there is also an item to make an item etheral

basically

A lot of this is for crafting, or crafting maps.... maps are just think of customized cow levels with modifers. you can buy the map materials of how you want to RNG craft them is act 5 anya just talk to her and its expensive why 50 stack of the main orb is worth .1 HR mal rune is a .1 HR KNOWING your currency is the biggest power to learn. 10 WSS shards you slam items with to change them or break them 10 of them worth .1 HR... ohm and vex is 1hr sur 1.25 the rest i forget some will argue ohm is only .75 but people need so many ohm you will find people that will pay 1hr for them.

the keys and organs obviously are for ubers and clones.

they needed this material stash for ever...... the dust all put together makes reset stats and skills. goes for a gul .25 hr. so good to farm them if u cant farm other things or keys. 3 key set like 3 sets of the 3 you can get a free anni or torch for keys. if you can key farm good.

crafting is fun in pd2. you will not fully benefit from fully crafting until level 88? until you can buy or loot items that are ilvl 88 - 91 there is a wiki dedicated to it that level you can get up to 6 affixs instead of 4. but if your crafting with rares anyways they can still be better but it doesnt really matter its all sper RNG PD2 is all RNG....... sometimes i find patterns in my farming but changes within a day or hour. I recommend get map ready to farm them materials and higher runes. My highest rune found is ohm in cow level. but it was one out of 50 or 100. no gul or ist. countess wont drop anything for me anymore. ugh. I think pd2 nerfed countess it use to be my go to.

but i heard they buffed anny act1 boss. so if you can farm her or mephoisto even though i havnt found crap not even a shako.

Thanks, this helps alot