My comment is not referring to D2:R, however I did try to use it with an Impale Zon and a Berserker Barb... the reason is simply because of the +4 Skills, ED, Psn Dmg, IAS and DS.
The zon has CS, so DS would also have a Hit Check. The Psn Dmg is similar to Bleed (monster can not regenerate hit points) and the +4 Skills to Passive Skills and Impale, Jab etc ... did not like Impale & Durability loss.
Now as for the Berserk barb using it... same sorta reasons, however never really gave it much thought, nor did I check if the Poison Damage hit check worked with a Magical Attack, thus did NOT spend that much time with it, since I get mass dmg using Grief in those days.
Oh, for bosses, I like to types of dmg with a melee character other than Crushing Blose... Bleed and Poison... so the bosses don't regen hit points etc.
Hope this helps a little.
EIDT: I never tried EBOTD anything... wasn't interested with grief being introduced in 1.10 just like Ariocs.
Omg arioc's on ama impale .............. i can't even imagine the damage xD And with crit xD How much damage does it clap off baal with a good roll? ^^ Can't even imagine. Baal has what, 600 000 hit points on p1? So like 10 000 dmaage x 2 ... shouldn't take too many hits to do the trick..... very cool thought.