It's good to document what you've tried.
Can you post PC specs and some more info about when you experience the crash? Does it happen 5 minutes after playing or 3 hours after playing, is it intermittent or have you noticed that certain things seem to make it crash more often (i.e. entering map portals or w/e).
What about other games? What other games do you play that works flawlessly or have issues with? You kinda need to slowly rule out different things that could be the cause, let's start with seeing if it's hardware or software related.
System specs:
Windows 10 pro
Version: 10.0.19045 build 19045
B660m Phantom Gaming motherboard
x64 PC based
i5-12700kf 3700mhz processor
32 gb ram
RTX3060 gfx
Hey, I have had an issue trying to play through the acts on a new character. I have the occassional crash or seven through the game normally but sometimes it'll get stuck on an instance and be unable to proceeed crashing immediately. Switching zones or swapping characters then swapping back does not fix it. I have to clean install to progress another 10-15 minutes. Happened at Renly with the reforging spikes in act 1, is currently happening at Halani Gates in act 2.
There will be a moderately acceptable amount of crashes during gameplay normally considering early access like 1 or 2 an hour, but often times it'll get locked in an instance and crash immediately or after any steps taken in an area with no way around or fix like in halani or with renly.