- A study published last week in the
Clinical Journal of Investigation shows that cannabis kills malignant cancer cells.
- Donald I. Abrams, MD et al. wrote in Feb. 13, 2007 article titled "Cannabis in Painful HIV-Associated Sensory Neuropathy: A Randomized Placebo-Controlled Trial" in the journal
Neurology:
Quote
Objective: To determine the effect of smoked cannabis on the neuropathic pain of HIV-associated sensory neuropathy, and an experimental pain model...
Patients were randomly assigned to smoke either cannabis (3.56% thc) or identical placebo cigarettes with the cannabinoids extracted three times daily for 5 days...
Conclusion: Smoked cannabis was well tolerated and effectively relieved chronic neuropathic pain from HIV-associated sensory neuropathy The findings are comparable to oral drugs used for chronic neuropathic pain.
- Derick T. Wade, MD, from the Department of Clinical Neurology at University of Oxford, et al. wrote in a Feb. 2003 article titled "A Preliminary Controlled Study to Determine Whether Whole-Plant Cannabis Extracts Can Improve Intractable Neurogenic Symptoms" in the journal
Clinical Rehabilitation:
Quote
OBJECTIVES: To determine whether plant-derived cannabis medicinal extracts (CME) can alleviate neurogenic symptoms unresponsive to standard treatment, and to quantify adverse effects...
Measures used: Patients recorded symptom, well-being and intoxication scores on a daily basis using visual analogue scales. At the end of each two-week period an observer rated severity and frequency of symptoms on numerical rating scales, administered standard measures of disability (Barthel Index), mood and cognition, and recorded adverse events.
RESULTS: Pain relief associated with both THC and CBD was significantly superior to placebo. Impaired bladder control, muscle spasms and spasticity were improved by CME in some patients with these symptoms. Three patients had transient hypotension and intoxication with rapid initial dosing of THC-containing CME.
CONCLUSIONS: Cannabis medicinal extracts can improve neurogenic symptoms unresponsive to standard treatments. Unwanted effects are predictable and generally well tolerated. Larger scale studies are warranted to confirm these findings.
-Maria L. de Ceballos, PhD, Researcher and Group Leade of the Department of Neural Plasticity at the Cajal Institute, Spain, et al. wrote in a Feb. 2005 article "Prevention of Alzheimer's Disease Pathology by Cannabinoids: Neuroprotection Mediated by Blockage of Microglial Activation" in the
Journal of Neuroscience:
Quote
Our results indicate that cannabinoid receptors are important in the pathology of AD [Alzheimer's Disease] and that cannabinoids succeed in preventing the neurodegenerative process occurring in the disease.
- In a study published in the journal
Nature ("Physiology: A Hunger for Cannabinoids") researchers Raphael Mechoulam et al. found:
Quote
[M]olecules found naturally in the body, as well as in cannabis -- stimulate appetite.
I have a few other journals on hand and will be posting more about the research on thc.
This post was edited by Gthumb420 on Apr 9 2009 09:54am