If I have different range modifiers on my weapons
I.e EBOTD collosus blade mainhand / Grief PB offhand
Will the PB be unable to hit if attacking at max range of the CB?

Can anyone explain the interaction or considerations for different weapon ranges for a Barb?

TYVM

When you hit range 2 weapon, your hit have +2 range. When you hit range 1 weapon, your hit have +1 range.

Real question is, why do you use / think using BOTD Colossus Blade on Frenzy Barb ?

Currently using 2 x grief pb, just wanted to switch it up.

Just keep your Grief PB’s

Do what you find fun. There are weapons other than grief that are better in specific situations . EDeath is nice for bosses, and I paid that with eBotd