one of the nice things about a thrower *hybrid* is that while zerk/howl destroys infector of souls & grand vizier of chaos with ease, zerk does not work so hot against lord de seis; he simply walks away from and WILL intentionally decrepify you if you attempt to melee him. Meanwhile, you can simple howl his minions and chuck axes at him and he'll just plain drop; he doesn't every run away if you stay at throwing distance from him. Likewise, while both zerk & throwers can kill diablo fairly easily, the amp damage from lacerators + frenzy from grief/beast will kill diablo almost retardedly fast, even in 8 player games.