The most important thing to take note of is that HM doesn't work in the Acc slot, only ee does. (as mentioned by Stok3d)
That eliminates almost all usefulness of a plain HM charm outside of catacomb games.
I used to own a 127ee, 24hm heal and it healed better than a 170ee heal. Perhaps that's some insight into Heal mastery for you.

In most cases HM is approximately 2x the healing effectiveness of EE or INT. I know that logic offends the people who want to crunch the exact formulas//numbers for this game, but it's good enough if you don't mind being off a percent here or there depending on a few other factors.
This post was edited by mwm_zyxcba on Mar 8 2010 08:25pm