If you're only doing catacombs: go for all heal mastery.
If you'll be only doing arena or doing both arena and catacombs: go for all intelligence.
Charm choice is all preference because they're all supposed to average the same, but I prefer focused because I always know exactly how but I'll be healing for. Wilds can be fun in catacombs sometimes but I would
not recommend trying to well with a wild heal until you're super skilled
But yeah, check out my guide
here and it will explain most of that stuff
feel free to PM me any additional questions you might have as well.