One key is the iron skin skill. It gives you 50% damage reduction for 4 seconds. This is the main time you have to tank, then you need to back out and get the skill off cooldown before going back in. What gets a lot of people is the rune you use lets you walk through enemies when you get hit, and this produces another iron skin icon on the "buff bar". This doesn't mean your 50% damage reduction is still going, just that you can walk through enemies.
Here's my build from season 4 when it was the top 'sader build:
http://us.battle.net/d3/en/profile/Crazy9000-1143/hero/69395799. It was good enough for a top10 clear at the time, GR70. The grifts have gotten easier since then, and there's hammer jammers now, so 75 should be very achievable without top gear.
Looking at your profile, you are missing cooldown. This is critical for survivability, so probably what is causing you the most trouble.