Is it possible to make gains on corticosteroids?

Vivi/cloudkicker/balla/lightman/etc. Please help. Studies/journals/knowledge from studying would be fantastic.

Really brax?

Really ladsy.

Been basically on and off of them for the past 2-3 years and I would like to get a better understanding about them. The help of intelligent people who know what their talking about and have a background with lifting would be fantastic to have.

i mean it will make life tough for you, its just another catabolic pressure on your body. i dont know if you have journal access through your school but this is a review of catabolic mechanisms due to glucocorticoids. Glucocorticoid-induced skeletal muscle atrophy O. Schakmana, S. Kalista, C. Barbé, A. Loumaye, J.P. Thissen,

its hard to say whether or not you can make it work, you have to optimize every other aspect of your training and existence in order to make sure you have ever opportunity to retain nitrogen

e: in general the article describes how glucocorticoids inhibit protein synthesis and upregulate protein metabolism through specific pathways and generally have degradation effects on fast twitch fibers compared to slow twitch fibers

This post was edited by cloudkicker on Sep 19 2015 11:41pm

send him the pdf if u troopa

Well taking corticosteroids is known to cause muscular atrophy

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911625/
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2362.2008.02067.x/full
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2265.1983.tb03198.x/full

The best I can assuredly say is that resistance training at least abrogates the atrophy

http://press.endocrine.org/doi/abs/10.1210/jcem-61-1-83

As for gaining muscle, I'd say it's possible, just more difficult. I'd be worried about insulin resistance if bulking as well tbh.

Simply put, look at the side effects of corticosteroids and make the decision yourself:

Elevated pressure in the eyes (glaucoma)
Fluid retention, causing swelling in your lower legs
Increased blood pressure
Mood swings
Weight gain, with fat deposits in your abdomen, face and the back of your neck
When taking oral corticosteroids longer term, you may experience:

Clouding of the lens in one or both eyes (cataracts)
High blood sugar, which can trigger or worsen diabetes
Increased risk of infections
Thinning bones (osteoporosis) and fractures
Suppressed adrenal gland hormone production
Thin skin, easy bruising and slower wound healing

(WEBMD)^

So basically when they say chronic use that means longer than 1 month sooo...lets see cataract because it probably fucks with the lens protein synthesis...high bp due to increased fluid retention...increased risk of infections (because your body's defense mechanisms are decreased/cell production decreased,etc), OSTEOPEROSIS/FRACTURES - probably due to osteoblast/osteoclast ratio being screwed with, so increased bone resorption (not good), decreased adrenal gland hormone production...similar to steroids and the testis shrinking, because all these CATABOLIC hormones are released from the adrenal gland (so decreased protein synthesis + fat absorption), and slower wound healing (typical of diabetes patients, same with the fact you can't fight off infections).

So basically overall, i THINK, they would be catabolic if you're lifting, and not good to take in general long term just because of the side effects....

Which exactly are you taking / at what dose? Pm me as i'll probably lose this thread.

Why are you taking them? ive been on them for the past month. Interested in more feedback

I have access to all journals through my school, so I will look into it when I have the time. Completely fell behind with schoolwork the past two weeks and shit.

Trying to work more on my nutrition aspect while going through this as I have already lost 10 pounds in the past 2 weeks. I have known for a while that they aren't that great for literally anything, but will definitely read more into this.

Hard to do resistance training with an impingement in my shoulder and every time I go on them, my shoulder immediately starts to feel worse.

Oh trust me, if I had the choice I would never touch them just because of the side effects.

Prednisone and currently on 40 mg. Also on Entyvio infusions. Humira injections were working, but I started having an allergic reaction. Mercaptopurine worked well for a few years and it just stopped being effective.

Ulcerative Colitis. Prepare to say goodbye to your gains and rational thinking.