Quote (EverNineAfter @ Apr 7 2011 04:19pm)
for a multivitamin, i read that NOW! Adam contains soy derivatives, from what i've been told / heard is that you should stay away from soy products etc, would this be a problem?
E: also in Orange triad, Vitamin A(as Alpha And Beta Carotene) 10000IU 200% now on wikipedia it says
β-Carotene and lung cancer in smokers
β-Carotene supplementation increases the probability of lung cancer in cigarette smokers. There are various competing theories as to the mechanism for this harmful effect of β-carotene supplementation in this group. The effect is specific to supplementation, as no lung damage has been detected in those who are exposed to cigarette smoke and who ingest a physiologic dose β-carotene (6 mg) in contrast to pharmacologic dose (30 mg). Therefore, the oncology from β-carotene is based on both cigarette smoke and high daily doses of β-carotene.[16]
A common explanation of the effect is that when retinoic acid is liganded to RAR-beta (Retinoic Acid Receptor beta), the complex binds AP1 (Activator Protein 1). AP1 is a transcription factor that binds to DNA and in downstream events promote cell proliferation. Therefore, in the presence of retinoic acid, the retinoic acid:RAR-beta complex binds to AP1 and inhibit AP-1 from binding to DNA. In that case, AP1 is no longer expressed, and cell proliferation does not occur. Cigarette smoke increases the asymmetric cleavage of β-carotene, decreasing the level of retinoic acid significantly. This can lead to a higher level of cell proliferation in smokers, and consequently, a higher probability of lung cancer.
Another β-carotene breakdown product suspected of causing cancer is trans-β-apo-8'-carotenal (common apocarotenal), which has been found in one study to be mutagenic and genotoxic in cell cultures which do not respond to β-carotene itself.[17]
now i dont smoke myself, but i am exposed to 2nd hand smoke everday and quite a lot, your thoughts?
Hey there. First of all, the amount of soy in any multivitamin is MARGINAL usually used for binding agents and so forth...no worries about that. Soy is bad for men when consumed in copious doses (like 100g a day or more).
As far as vitamin A and cancer goes - there is a TON of evidence to support vitamin a actually reducing the risk of most kinds of cancers.
Increasing the risk in smokers is specious at best because you must remember that smokers are already at risk to begin with. If you do not have a genetic predisposition to cancer, and do not smoke yourself you will MOST LIKELY not get lung cancer no matter what.
lastly, second hand smoke has been proven in many independent studies to contain such a trace amount of carcinogens that it is not nearly as harmful as direct inhalation. Sure, it would be better to avoid it all together, but right now it won't harm you I'm sure.