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Jun 17 2015 01:52pm
"Influence of resistance exercise intensity and metabolic stress on anabolic signaling and expression of myogenic genes in skeletal muscle"

http://onlinelibrary.wiley.com/doi/10.1002/mus.24314/abstract

Differential anabolic signaling via metabolic stress. Building a molecular framework by which metabolic stress factors into hypertrophy w/in the other components. Questions arising: is it redundant? synergistic? additive?

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Jun 17 2015 08:40pm
its got a bit of cell bio but its more of a personal statement

this guy literally took these thoughts from my head, he is now my hero

http://startingstrength.com/articles/barbell_medicine_sullivan.pdf
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Aug 25 2015 10:03am
Resurrection complete.
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Aug 26 2015 01:23am
"Rethinking the role of fat oxidation: substrate utilisation during high-intensity interval training in well-trained and recreationally trained runners"

http://bmjopensem.bmj.com/content/1/1/e000047.full

"Conclusions Despite similar RPE, blood lactate and carbohydrate oxidation rates, the better performance by the WT group was explained by their nearly threefold higher rates of fat oxidation at high intensity."

So the well-trained groups were similar to recreationally trained groups in perceived exertion, blood lactate, and CHO oxidation rates in a bout of HIIT. Where the difference manifested was in fat oxidation being so markedly higher in well-trained individuals. They also note, " Higher rates of fat oxidation had a very large correlation with VO2max (r=0.86; 90% CI (0.7 to 0.94)."

Relevant. Interesting.
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Aug 27 2015 11:23pm
Any evidence showing lower reps to be better at maintaining muscle mass at a caloric deficit, or is that purely logic based information? I found studies that showed no difference but none showing low reps superior.

Also anyone read about the cancer curing drug dichloroacetate?
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Aug 28 2015 06:35am
Quote (tommyd323 @ Aug 28 2015 01:23am)
Any evidence showing lower reps to be better at maintaining muscle mass at a caloric deficit, or is that purely logic based information? I found studies that showed no difference but none showing low reps superior.

Also anyone read about the cancer curing drug dichloroacetate?


http://www.cancer.org/aboutus/drlensblog/post/2010/05/14/more-on-dichloroacetate-%28dca%29-in-cancer-treatment.aspx
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Aug 28 2015 02:19pm
Quote (tommyd323 @ Aug 28 2015 01:23am)
Any evidence showing lower reps to be better at maintaining muscle mass at a caloric deficit, or is that purely logic based information? I found studies that showed no difference but none showing low reps superior.

Also anyone read about the cancer curing drug dichloroacetate?


Yeah, studies on this are scarce to non-existent.
Tbh, I've slightly changed my stance on this compared to before. We know volume is the most important variable in promoting muscle growth and impeding muscle degradation. As such, lowering reps far down is going to immediately cause a drop in volume. Your goal in cutting is still to "gain muscle" insofar that you're aiming to augment protein synthesis rates and attenuate protein degradation rates as much as possible, just in the face of a deficit. I think if we're talking about going 15+ reps consistently, that will cause a hindrance in maintaining maximal muscle. However, if we're talking about the difference between 4-5 rep sets and 8-10, I really doubt it's going to change to an appreciable degree. I'd say the overall anabolic stimulus of lifting, period, will largely circumvent this. It also may depend on how large your deficit is. The larger the deficit, the more I would assume lower volume and higher intensity would come into play, simply because you can't recover as well. In other words, the more volume you can sustain and RECOVER from whilst cutting, the more muscle you will likely hold onto. A problem with keeping volume sufficient whilst increasing intensity (rm%) could lead to cns fatigue more celeritously. It's also true you shouldn't go excessively light. But let's also take note of that fact that occlusion training shows ability to retain mass in a deficit state.
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Aug 29 2015 09:50am
Quote (Balla @ Aug 28 2015 03:19pm)
Yeah, studies on this are scarce to non-existent.
Tbh, I've slightly changed my stance on this compared to before. We know volume is the most important variable in promoting muscle growth and impeding muscle degradation. As such, lowering reps far down is going to immediately cause a drop in volume. Your goal in cutting is still to "gain muscle" insofar that you're aiming to augment protein synthesis rates and attenuate protein degradation rates as much as possible, just in the face of a deficit. I think if we're talking about going 15+ reps consistently, that will cause a hindrance in maintaining maximal muscle. However, if we're talking about the difference between 4-5 rep sets and 8-10, I really doubt it's going to change to an appreciable degree. I'd say the overall anabolic stimulus of lifting, period, will largely circumvent this. It also may depend on how large your deficit is. The larger the deficit, the more I would assume lower volume and higher intensity would come into play, simply because you can't recover as well. In other words, the more volume you can sustain and RECOVER from whilst cutting, the more muscle you will likely hold onto. A problem with keeping volume sufficient whilst increasing intensity (rm%) could lead to cns fatigue more celeritously. It's also true you shouldn't go excessively light. But let's also take note of that fact that occlusion training shows ability to retain mass in a deficit state.



Yeah I was talking 15-20+ reps to tone your arms lol
I wouldn't think 8-10 would make much difference either consisting 7 was the ideal number one of u guys had before.
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Aug 31 2015 01:36pm
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Sep 1 2015 01:43am
Any studies done to test hormonal changes from no-fap kind of stuff? chi kung says you lose qi out the yin yang and 1 drop of semen is worth 1000 drops of blood (thirsty hnf?)

Quote (tommyd323 @ 31 Aug 2015 14:36)


the broscience is to pound casein before bed cuz it's slow release feed dem gainz even when we sleep :zzz:
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