Copy/pasting from suppversity
Pretty good back and forth discussion on muscular atrophy though
What is everyone's thoughts on the issue? Attenuated MPS or augmented MPB?
SuppVersity Suggested: Cross-Talk - What causes muscle atrophy? A lack of protein synthesis or an increase in proteolysis (protein breakdown) - Read the two article and rebuttals in the Journal of Physiology (links below)
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CrossTalk proposal: The dominant mechanism causing disuse muscle atrophy is decreased protein synthesis
Stuart M. Phillips and Chris McGlory
J Physiol December 15, 2014 592 (24) 5341-5343; doi:10.1113/jphysiol.2014.273615
http://jp.physoc.org/content/592/24/5341CrossTalk opposing view: The dominant mechanism causing disuse muscle atrophy is proteolysis
Michael B. Reid, Andrew R. Judge, and Sue C. Bodine
J Physiol December 15, 2014 592 (24) 5345-5347; doi:10.1113/jphysiol.2014.279406
http://jp.physoc.org/content/592/24/5345Rebuttal from Stuart M. Phillips and Chris McGlory
Stuart M. Phillips and Chris McGlory
J Physiol December 15, 2014 592 (24) 5349; doi:10.1113/jphysiol.2014.284406
http://jp.physoc.org/content/592/24/5349Rebuttal from Michael B. Reid, Andrew R. Judge and Sue C. Bodine
Michael B. Reid, Andrew R. Judge, and Sue C. Bodine
J Physiol December 15, 2014 592 (24) 5351; doi:10.1113/jphysiol.2014.284398
http://jp.physoc.org/content/592/24/5351