Question About Half Life Times And Effects? - Topic

carteblanche

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#21

Nov 24 2014 12:49am

Quote (Lancet_Jade @ Nov 24 2014 12:26am)

Weed, ty

cant you just buy it from a vending machine these days?

Balla

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#22

Nov 24 2014 12:57am

Quote (ViviLOL @ Nov 24 2014 02:47am)

Did not know this, thank you.

I personally noticed it for myself when I began using melatonin alongside my weed right before I lay down and fall asleep. I began vividly remembering my dreams again which I hadn't noted for awhile, indicative of rem dysfunction. So the melatonin definitely isn't used for sleep latency purposes in this case, purely for quality purposes

MrBobMarley

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#23

Nov 24 2014 01:17am

Quote (Balla @ Nov 24 2014 06:57am)

Definitely this with the dreaming.

Just the melatonin itself helped. Haven't really dreamed much the past couple years. Now somewhat regularly. wake up more refreshed as well.

YoloSwag420

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#24

Nov 24 2014 09:28am

Quote (Lolzor @ Nov 24 2014 01:17am)

well, really you should prepare to deal with a family physician regarding this...
information you would discuss would be things like sleeping habits, drugs you have tried (and any successes/failures/adverse events like a possible hangover effect I am guessing from the Benadryl lol) and any conditions/allergies/history of your insomnia.

it is a pretty common issue and there are tons of drugs to look into based on your preferences (how long do you need to sleep, your occupation (being tired the next morning could be dangerous), your lifestyle, your family choices, any other coexisting conditions which could be treated (IE treating depression and insomnia with trazodone or anxiety + insomnia with a benzodiazepine) etc.

there are a million different details to identify the best treatment, but some common ones include:
Ambien
Lunesta or Imovane
Benzos
Trazodone
etc.

GG
This.

Also: Sex is a great way to help some people fall asleep.

cloudkicker

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#25

Nov 24 2014 10:46am

Half Life is just a measure of how long it takes for plasma drug concentration to drop by 50 percent. Half Life time varies depending on a couple of factors that balla touched on, which ultimately influence rxn kinetics in the liver. The faster the liver can metabolize a drug the shorter the half life. The effect is not directly proportional to plasma concentration however. There is a thing called a therapeutic range for each compound, the upper boundary denotes the dose at which toxicity effects kick in and the lower boundary is the minimum concentration at which you even notice a benefit from the drug. 50mg may get you into the therapeutic range but after 1 or 2 half lives you may not have enough drug in the target tissue to take any benefit

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