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Jan 21 2015 11:43pm
Quote (Shakti @ Jan 22 2015 01:28am)
Right. I bought a cheap setup so as soon as any negative side effect related to vaping start popping up I won't hesitate to throw it out


what if those negative effects mostly come from cheaply made vape thing a ma bobbers?

and why wait till they find out how bad they r?
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Jan 22 2015 12:07am
I recall a friend saying they're more addicting cause they have more nicotine than cigs so if you ever quit and go to cigs you'll need more...
also why vape at all
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Jan 22 2015 07:55am
Quote (FxG @ Jan 22 2015 02:07am)
I recall a friend saying they're more addicting cause they have more nicotine than cigs so if you ever quit and go to cigs you'll need more...
also why vape at all



Not even close. The robust addictive properties of cigs are more-so a product of the synergistic effect of the nicotine in combination with the presence of a plethora of monoamine oxidase inhibitors, beta carbolines for instance.

Now granted, nicotine is slightly addictive on its own, but w/ the MAOIs it's pretty incomparable. Nicotine will of course release some mesolimbic dopamine secretion to promote that activity, plus in the longer term, will upregulate kappa opioid receptors (which attenuates the DA secretion), and will act as the pharmacological chaperone to upregulate alpha-4/beta-2 nicotinic ACh receptors. All these changes promote the reinforcement and subsequent desire for more, though to reiterate, the MAOIs synergistically increase that. Plus, nicotine generally isn't all that bad for your health, on its own at least. Cigs have the carcinogenic nitrosamines to mediate most of their deleterious effect.
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Jan 22 2015 08:34am
Quote (Shakti @ Jan 22 2015 01:28am)
Right. I bought a cheap setup so as soon as any negative side effect related to vaping start popping up I won't hesitate to throw it out


How do you know damage hasn't been done at or before that point?
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Jan 22 2015 08:34am
Quote (shane_is_a_balla @ Jan 22 2015 08:55am)
Not even close. The robust addictive properties of cigs are more-so a product of the synergistic effect of the nicotine in combination with the presence of a plethora of monoamine oxidase inhibitors, beta carbolines for instance.

Now granted, nicotine is slightly addictive on its own, but w/ the MAOIs it's pretty incomparable. Nicotine will of course release some mesolimbic dopamine secretion to promote that activity, plus in the longer term, will upregulate kappa opioid receptors (which attenuates the DA secretion), and will act as the pharmacological chaperone to upregulate alpha-4/beta-2 nicotinic ACh receptors. All these changes promote the reinforcement and subsequent desire for more, though to reiterate, the MAOIs synergistically increase that. Plus, nicotine generally isn't all that bad for your health, on its own at least. Cigs have the carcinogenic nitrosamines to mediate most of their deleterious effect.


Thanks!
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Jan 22 2015 08:42am
How about you just stop being an idiot and don't smoke anything. I've never understood how someone can be so dumb and actually want to inhale that shit.


Also huge waste of money. :bonk:

This post was edited by Orakpo on Jan 22 2015 08:43am
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Jan 22 2015 10:46am
Quote (Orakpo @ Jan 22 2015 10:42am)
How about you just stop being an idiot and don't smoke anything. I've never understood how someone can be so dumb and actually want to inhale that shit.


Also huge waste of money. :bonk:


tabbaccy is wacky

other shit who knows ! :drool:

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Jan 22 2015 01:22pm
Still contains nicotine.
Still will become addicted
Still negative to your body.

Better then cigarettes, but still bad.

I'll compare it to deadlifting.

Smoking a cigarette is like deadlifting too much weight with a rounded back.
Vaping is like deadlifting 135 with a rounded back.

Still bad for your body, but not as bad as cigarettes.
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Jan 22 2015 02:08pm
cigarettes>
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Jan 22 2015 02:15pm
Lol vaping is stupid. How are you going to expect putting chemicals in your lungs to not have any side effects?
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