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Dec 16 2014 10:10pm

Doxylamine succinate (12.5 mg/30 mL) (antihistamine/hypnotic)


First generation antihistamines cause drowsiness when the enter the brain and affect histamine receptors among other things... they aren't highly selective and histamine is needed within the brain to aid in wakefulness.
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Dec 16 2014 10:12pm
Quote (fingerling @ Dec 17 2014 04:04am)
I am biochemist 8% body fat des all u needa no

And I like


I make a thread about wanting to know mechanism to biological process and somehow JM suicidal


Seems like story of lightman's life.

If you are not him I'd pm for advice
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Dec 16 2014 10:15pm
Few mechanisms by which it can impede libido

The dextromethorphan acts as a serotonin reuptake inhibitor, which may act via 5-HT2 & 3 receptors to diminish dopaminergic transmission through certain mesolimbic pathways which facilitate desire/wanting/motivation for that and thus libido.
The doxylamine acts as both an anticholinergic and antihistamine, both of which impede erection & libido
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Dec 16 2014 10:23pm
The only time I drank NyQuil was at 5 o'clock in the morning when I was coming down from MDMA and LSD.
Which I was woken up four hours later to check out the hotel and it felt like I took 4mg of Xanax.

This post was edited by S3th on Dec 16 2014 10:24pm
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Dec 16 2014 10:28pm
Quote (S3th @ Dec 17 2014 04:23am)
The only time I drank NyQuil was at 5 o'clock in the morning when I was coming down from MDMA and LSD.
Which I was woken up four hours later to check out the hotel and it felt like I took 4mg of Xanax.


I think the mdma/lsd come down contributed a lot to nyquil acting as a very short acting/high dose of a benzo lol!

if nyquil did that oh lawd
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Dec 16 2014 10:31pm
Quote (S3th @ Dec 16 2014 11:23pm)
The only time I drank NyQuil was at 5 o'clock in the morning when I was coming down from MDMA and LSD.
Which I was woken up four hours later to check out the hotel and it felt like I took 4mg of Xanax.


Ywh I just take it when I wake up and before I go to bed. and maybe a shot I'm the kiddle of the day.
Can't take being in my rihght mind. Too much pain
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Dec 16 2014 10:33pm
Quote (ug_warrior(xtc) @ Dec 16 2014 11:28pm)
I think the mdma/lsd come down contributed a lot to nyquil acting as a very short acting/high dose of a benzo lol!

if nyquil did that oh lawd


I'm unsure but I took the NyQuil at least 6 hours after dosing MDMA.
Which is probably best because I didn't even think about how they could have interacted; which is very unlike me.

Quote (fingerling @ Dec 16 2014 11:31pm)
Ywh I just take it when I wake up and before I go to bed. and maybe a shot I'm the kiddle of the day.
Can't take being in my rihght mind. Too much pain


You should really see about going to therapy.
It's a pretty great experience :D

This post was edited by S3th on Dec 16 2014 10:34pm
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Dec 16 2014 10:34pm
Quote (Balla @ Dec 16 2014 11:15pm)
Few mechanisms by which it can impede libido

The dextromethorphan acts as a serotonin reuptake inhibitor, which may act via 5-HT2 & 3 receptors to diminish dopaminergic transmission through certain mesolimbic pathways which facilitate desire/wanting/motivation for that and thus libido.
The doxylamine acts as both an anticholinergic and antihistamine, both of which impede erection & libido


/thread
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Dec 16 2014 10:36pm
Quote (S3th @ Dec 17 2014 04:33am)
I'm unsure but I took the NyQuil at least 6 hours after dosing MDMA.
Which is probably best because I didn't even think about how they could have interacted; which is very unlike me.


when you're in the molly zone bra and you start to fall out of it (never hippy tripped, mdma/lsd same time) you wanna die lol. mdma come down is awful I'd take anything to sleep through it, too. lots of people take an ssri/snri to follow up next day cuz serotonin is depleted as fucccck

Quote (fingerling @ Dec 17 2014 04:31am)
Ywh I just take it when I wake up and before I go to bed. and maybe a shot I'm the kiddle of the day.
Can't take being in my rihght mind. Too much pain


sounds like you're shooting tar now wtf lol

This post was edited by ug_warrior(xtc) on Dec 16 2014 10:37pm
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Dec 16 2014 10:38pm
Quote (ug_warrior(xtc) @ Dec 16 2014 11:36pm)
when you're in the molly zone bra and you start to fall out of it (never hippy tripped, mdma/lsd same time) you wanna die lol. mdma come down is awful I'd take anything to sleep through it, too. lots of people take an ssri/snri to follow up next day cuz serotonin is depleted as fucccck



sounds like you're shooting tar now wtf lol


Yeah, I know.
I'm pretty sure most take 5-HTP afterwards.
I'm aware that taking too much 5-HTP before can lead to serotonin syndrome or just being on any SSRI.
And honestly, most of my MDMA come downs were peacefully pleasant.
I was just wired awake / hungover feeling and a little out of it.

This post was edited by S3th on Dec 16 2014 10:39pm
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