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Jan 6 2015 12:13pm
So I have crohns/ulcerative colitis and have been on and off corticosteroids for quite some time. I got off of them about a month and a half ago. I started lifting again, starting like 3-4 weeks ago and now I'm back on the corticosteroids. My doctor told me that i could lift on them, but everything I have read online has said that it is a terrible idea.

I know there are a few people in here who are really intelligent and some also in the medical field/human body type of work. I'm just looking for a second opinion on if I should stop or if it's okay.

This was typed on my phone, so I apologize if it's a little sporadic.
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Jan 6 2015 01:13pm
Indeed, I would lift simply to mitigate the loss of bone & muscle tissue and try to stave off excessive fat gain.

Also, are your corticosteroids administered following the normal circadian response? EIther way, I feel the use of corticosteroids actually worsens Crohn's disease (obv it's prescribed bc anti-inflammatory). I would opt for other treatments, marijuana for one.
Essentially, chronic cortisol will attenuate collagen synthesis and promote its destruction in the gut (everywhere actually but there specifically here). Long-story short, this promotes a redox shift and more intestinal permeability (bad), which then later after some other changes shifts zonulin, promoting more intestinal permeability and the subsequent presence of immune filtration (via GALT) and promotion of the autoimmune disease in genetically prone individuals. This will worsen your condition overall by attacking the same system that promoted this malfunction in the first place.

This post was edited by shane_is_a_balla on Jan 6 2015 01:21pm
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Jan 6 2015 01:21pm
Quote (shane_is_a_balla @ Jan 6 2015 03:13pm)
Indeed, I would lift simply to mitigate the loss of bone & muscle tissue and try to stave off excessive fat gain.

Also, are your corticosteroids administered following the normal circadian response? EIther way, I feel the use of corticosteroids actually worsens Crohn's disease (obv it's prescribed bc anti-inflammatory). I would opt for other treatments, marijuana for one.
Essentially, chronic cortisol will attenuate collagen synthesis and promote its destruction in the gut (everywhere actually but there specifically here). Long-story short, this promotes a redox shift and more intestinal permeability (bad), which then later after some other changes shifts zonulin, promoting more intestinal permeability and the subsequent presence of immune filtration (via GALT) and promotion of the autoimmune disease in genetically prone individuals. This will worsen your condition overall but attacking the same system that promoted this malfunction in the first place.


I was supposed to start Humira (a biologic), but I have been dicked around by insurance companies and everything else and my doctor took me off my old medicine because he was expecting me to be on Humira right away and the two are really bad when mixed. I have been essentially on no meds for 3 or so weeks and I have gotten really bad, which is why I am back on prednisone. This prednisone is not by choice, it is simply because I can't do anything at the moment.

I also asked my doctor about the marijuana and he won't support it till it is more than just case studies.
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Jan 6 2015 02:42pm
I don't see any harm in exercising while on prednisone unless you are going balls-to-the-wall, in which case it might be more damaging, especially for things like your joints.
It will be beneficial at helping your body to regulate bone turnover and blood sugar levels which are altered by corticosteroids and may also help to stave off some unwanted weight gain.
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Jan 6 2015 04:33pm
Quote (Braxton11 @ Jan 6 2015 02:13pm)
So I have crohns/ulcerative colitis and have been on and off corticosteroids for quite some time. I got off of them about a month and a half ago. I started lifting again, starting like 3-4 weeks ago and now I'm back on the corticosteroids. My doctor told me that i could lift on them, but everything I have read online has said that it is a terrible idea.

I know there are a few people in here who are really intelligent and some also in the medical field/human body type of work. I'm just looking for a second opinion on if I should stop or if it's okay.

This was typed on my phone, so I apologize if it's a little sporadic.


what have you read that said it was a bad idea
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Jan 6 2015 05:31pm
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EIther way, I feel the use of corticosteroids actually worsens Crohn's disease


I've stopped reading here
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Jan 6 2015 05:38pm
Quote (Urbain @ Jan 6 2015 07:31pm)
I've stopped reading here


Lack of education of the pathophysiology of the disease in the first place, you ignorant and hubristic medical student (as usual)
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Jan 6 2015 07:19pm
Quote (YoloSwag420 @ Jan 6 2015 04:42pm)
I don't see any harm in exercising while on prednisone unless you are going balls-to-the-wall, in which case it might be more damaging, especially for things like your joints.
It will be beneficial at helping your body to regulate bone turnover and blood sugar levels which are altered by corticosteroids and may also help to stave off some unwanted weight gain.


Quote (cloudkicker @ Jan 6 2015 06:33pm)
what have you read that said it was a bad idea


It is the exact opposite of anabolic steroids. The whole catabolic thing and your body takes forever to recover while on them. I've had bruises for over 2 weeks.

Doesn't it take longer for your muscles to recover?
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Jan 6 2015 09:16pm
Quote (shane_is_a_balla @ Jan 6 2015 06:38pm)
Lack of education of the pathophysiology of the disease in the first place, you ignorant and hubristic medical student (as usual)



A+

08 with 160 posts comes out of left field with a gg response to op question
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Jan 6 2015 10:11pm
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