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Oct 5 2014 04:39am
Would the effects of an antidepressant such as Valdoxan (agomelatine) (used for depression/social anxiety) be negated by smoking cannabis, albeit a minuscule amount (1 cone)
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Oct 5 2014 08:56am
Das like saying vodka (depressant) cancells out redbull (stimulant)


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Oct 5 2014 09:07am
Quote (HotHamAndCarl @ Oct 5 2014 09:56am)
Das like saying vodka (depressant) cancells out redbull (stimulant)


no it makes you feel invincible...

i remember them days of working my 2 jobs, 1 at starbucks waking up in the morning with some canni, go to work, drink espresso, take a break more canni, come back to work, more canni.

talk about one of the best "highs" you could ever have. literally felt invincible...
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Oct 5 2014 09:31am
Quote (HotHamAndCarl @ Oct 5 2014 10:56am)
Das like saying vodka (depressant) cancells out redbull (stimulant)


well done ladsy, pharmacology is not so straightforward
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Oct 5 2014 01:59pm
Quote (cloudkicker @ 5 Oct 2014 08:31)
well done ladsy, pharmacology is not so straightforward


LOL
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Oct 5 2014 02:13pm
Quote (HyphyIll @ Oct 5 2014 03:59pm)
LOL


I was being sincere too though a lot of people think that things just cancel eachother out if taken together when it's typically way more complex than that
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Oct 5 2014 03:38pm
They will both interact at least in one of the stages to create an action potential.
Your best bet is to look into what other people have experienced.
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Oct 5 2014 07:42pm
Quote (S3th @ Oct 6 2014 07:38am)
They will both interact at least in one of the stages to create an action potential.
Your best bet is to look into what other people have experienced.


Yup google doesn't have any conclusive shit. FYI I'm not talking about the effects on the high, but rather the effects on my mental health.



I read that depression could be highly linked to low levels of serotonine. And when smoking weed you get an increase, followed by a significant drop.

Now, if this antidepressant is supposed to balance out the chemicals, but I keep smoking weed (which may have been partly the cause of my problems), would it actually negate the effects of the antidepressant.

Balla knows chemicals, balla knows weed, I'm hoping balla knows these chemicals + weed and whether or not it could be cause for concern.. Or if 1 cone, every second day won't do shit
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Oct 5 2014 08:01pm
Quote (FrozenWater @ Oct 5 2014 08:42pm)
Yup google doesn't have any conclusive shit. FYI I'm not talking about the effects on the high, but rather the effects on my mental health.



I read that depression could be highly linked to low levels of serotonine. And when smoking weed you get an increase, followed by a significant drop.

Now, if this antidepressant is supposed to balance out the chemicals, but I keep smoking weed (which may have been partly the cause of my problems), would it actually negate the effects of the antidepressant.

Balla knows chemicals, balla knows weed, I'm hoping balla knows these chemicals + weed and whether or not it could be cause for concern.. Or if 1 cone, every second day won't do shit


What type of Anti-Depressant are you on?
Serotonin and Dopamine are implicated in Depression.
Marijuana does produce an increase in serotonin then after levels drop to a lower point than what they were at baseline.
It would depends on what type of anti-depressant you are on.
For example: If you're taking SSRIs then it may have little to no affect due to your body not producing serotonin at normal rates where it would even take advantage of blocked re-uptake.
SNRIs may bring back to baseline or higher but I'm unsure if the increase in serotonin from both would cause any physical/psychological harm.

Are you in therapy for your depression?

I would just consult with a trained mental health professional.

This post was edited by S3th on Oct 5 2014 08:16pm
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Oct 5 2014 08:24pm
Quote (S3th @ Oct 6 2014 12:01pm)
What type of Anti-Depressant are you on?
Serotonin and Dopamine are implicated in Depression.
Marijuana does produce an increase in serotonin then after levels drop to a lower point than what they were at baseline.
It would depends on what type of anti-depressant you are on.
For example: If you're taking SSRIs then it may have little to no affect due to your body not producing serotonin at normal rates where it would even take advantage of blocked re-uptake.
SNRIs may bring back to baseline or higher but I'm unsure if the increase in serotonin from both would cause any physical/psychological harm.

Are you in therapy?

I would just talk to your Doctor after all, he is a Doctor.
Balla and I are not but that's information I can give.


Not sure on what type of medication it is, other than that it's Valdoxan (agomelatine).

Not in therapy, dr said id only need to consider that if I didn't get any better after my course of these. Especially because I don't have any obvious issues rooted deep into childhood or anger issues.

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