as much mob debuff and character multiplier from tomes
if you can reach 500% of each, then you will only need like 1-2b relics to put in dmg, hit, dodge, crit dmg, crit chance, w, t, f damage in a ratio like 3:1:1:3:3:1:1:1 (yes, 0 points to hp, you don't need that for guardians)
if not, then upgrade your store and closet, get more tome slots, cuz without debuff and multi g5 would even require as much as 30b relics