If you’ve got multiple CD keys/accounts, you can run more than one D2R at the same time; you just have to open a separate game client for each account.
The usual way people do it is:
-install or copy the game folder twice so you have two separate launchers
-open each one and log into a different account/CD key
-then just alt tab between them. One can be your BO barb, the other your main
-as long as you control each character manually (no automation or key mirroring stuff), you’re good
If you want AFK characters in your game for XP, you can bring them in the same way; just leave them parked. Just don’t use bots or macros to move them around.
It’s pretty simple once you have separate accounts: one client per account, alt tab to swap, done. 👋