anywhere before guild hall in nightmare on softcore is doable with a smiter, and anywhere beyond that is insanely impossible or close to it, non elite mode
i re-spec'ed my smiter into a tank, for party play/SoR.
since i had boosted 60:40 int/vit, i have enough mana with all my AA gear too, to cast and spell all of these "Mana-draining" attacks on it
i think i have horrible resist though, which means = death , especially in any area after guild hall, or anywhere at st.pauls
the 5 lies, is nearly impossible for a smiter, even with 5 of them with the best gear i think. ( just depends, if you're Full shield skills or not )
i have zero shield skills now on my guardian dough