does anyone else have issues when trying to shrine?
When I click it in town it does open my inventory instead.

It should open both the inventory and the shriner drop box. Is your shrine box hidden behind the inventory?

nope. I've tried to move all boxes around. and also tried to open shrine with hotkey. doesn't help either

Hmm, weird. Maybe trying clearing cache to reset settings and see if that helps?

Obviously you can't shrine anything without your inventory open hence why your inventory is getting opened. My guess is that you've moved your shrine window out the way somewhere.

Can we get a full screenshot of logging out followed by logging in then clicking the shrine?

Logging out of ls and back in should make sure all Windows are closed

Maybe ur not full window and the shrine is "out of your visible area".

Try to maximize ur window and zoom out a bit

I actually thought about this earlier, and if this was the case, the OP should just adjust their ZOOM on what they are using, Chrome / Mozilla (firefox) etc vs their PC specs (graphics etc).

All windows (open or not for LS) will automatically fit within the Screen parameters.

Okay... I use 100% Zoom on Chrome, but my Screen specs are limited. Currently, I don't like my inventory window covering my catacomb because my settings are limited... so, the OPs settings are outstide of the limit.

Remember, I am agreeing with you in your response, I am just trying to give another view on the other scale of the OP's Settings.