Sickle cell was already heavily crisprfied...
Should they crispr human malaria next?
https://phys.org/news/2025-01-chimpanzees-genetically-local-habitats-infections.ampQuote
The scientists compared the genetic information to data about the local environment each chimpanzee population lives in, identifying genetic variants that stand out as being much more frequent in certain regions than others, and that likely confer a benefit to those carrying the genetic variant in particular habitats.
The scientists found evidence of genetic adaptation in genes related to certain pathogens (disease-causing microorganisms) among the chimpanzees living in forests, where there is a high concentration of pathogens, with the strongest evidence found in genes linked to malaria. This includes two genes that are also known to be responsible for adaptation and resistance to malaria in humans: GYPA and HBB, the latter being responsible for sickle cell anemia in humans.
The findings suggest that malaria is likely a significant disease for wild forest chimpanzees and that adaptation to the malaria parasite has happened, independently, through changes in the very same genes in chimpanzees and humans.