Quote (ChaunceyCulpeppa @ Feb 20 2024 08:00pm)

its DRG* survivor. just came out last week i believe

Quote (KevlarKondom @ 20 Feb 2024 23:04)

Oh okay. Just looked it up. Yeah that's a different version of original DRG. DRG is single player/co-op and a FPS.

Looks like DRG combined with Vampire Survivors, which I feel like is a new genre since that game came out. Looks kinda cool. Might pick it up this weekend.

Quote (ChaunceyCulpeppa @ Feb 20 2024 10:09pm)

thats exactly what it is. im really enjoying it rn

Quote (powwpoww @ 24 Feb 2024 17:02)

Quote

The B-cell-focused therapy is currently being tested in lupus, systemic sclerosis, myasthenia gravis and multiple sclerosis.

Quote

Multiple sclerosis is the clear market behemoth, but it wouldn't be the fastest route. Maag touted the early efficacy signal seen in one myasthenia gravis patient, reported on in The Lancet Neurology.

Quote

Copy-paste genetics
Usually, the sequence of an individual's gene is inherited from their parents, but in some circumstances, part of a gene sequence can be copied between different genes on the same DNA molecule—this is known as non-allelic gene conversion. This process has been linked to the evolution of important gene families, including those involved in the functioning of the human immune system.

One of this study's key discoveries is that gene conversion takes place between the P. falciparum DBLMSP and DBLMSP2 genes and results in increased genetic diversity within the surface proteins of the parasite. Since these proteins are exposed to, and interact with our immune system, they are potential vaccine targets, and a fuller understanding of their genetic diversity could be very valuable for vaccine design.

"The discovery of 'copy-paste' genetics within malaria's DNA reveals the impact of an underestimated evolutionary mechanism," said Brice Letcher, Postdoctoral Researcher at the Laboratory for Biology and Modeling of the Cell (LBMC, France) and former Ph.D. student at EMBL-EBI.

Quote

In the end, they identified 25 genomes from ruminants and another 22 from humans. An evolutionary analysis suggested there were four distinct groups of cellulose-digesting species in humans.