1. how did Columbus's relationship to the Spanish crown changed over time, and why?
2. Why did Columbus's voyages lead to permanent European settlement in the Americas, whereas the tenth-century Viking voyages did not?
3. Assess the significance of European maritime technology and superior weaponry in making the Enterprise of the Indies possible.
4. Analyze the consequences of the exchange of food plants, animals, and diseases among Eurasia, Africa, and the Americas after 1492.