First off the catapult is you best tower. I pretty much only had them, well and a couple snowball towers. Build a basic maze with catapults and then fully upgrade them.
Now for the cheating part.
Right after they fire, hit the pause button. The mobs will freeze, but your towers will continue to reset to get ready for another shot, and once they do, unpause, let them fire, and then pause again and repeat this step until the mobs are dead.
Doing this will let you destroy any mobs before they really get a chance to move, thus simplifying the game even more than it already is.