Hmm, for 75, if I can use stats and skills (of course the way you wish)... say a high (I don't count ist or gul there tho) rune before and one after (ie, 2 all in all)?
10%? Even if used all that on a barb, till level 80 that's only 8*5*4=160 life, no? That's harsh to survive on, but if you provide str and life charms to get enough str to wear equip and enough life to survive a hit (that means at least 600) I guess it doesn't have to get extremely expensive, but you'd be looking at over 2 high runes.