What artifacts / offensive costume affixs / medals are the best choice for Cyclops?
Also what should I look for on my gear?
THANKS!!

Bump

Doctor Octopus Medallion for greater area or MODOK medallion for damage.

Depends on the build you're going with.

I'm all about Optic Devastation... It's a pretty secular build, it's devoid of all attack speed--I'm going for as much defense penetration and pure damage as I can get. Basically that means Doc Oct Medal/Medallion, Metasensory Array & Power Prism Shard; stacking crit chance and trying to make the radius and range as large as possible. Defense is an issue, so I grabbed plenty of dodge chance, and defense.

Now I suspect most Cykes are running around with ATK SPD & Crit Chance, most likely using Optic Blast synergy (probably Optic Blast as main single target skill).

Don't worry about additional spirit, he doesn't need it, there's a skill for that and you'll find lots of -% to spirit cost. I skipped the fighting tree, except for one dodge skill and Uncanny Force (+1 each). Tactics use as you will, I maxed two party buffs (Tactical Command and it's DEF Buff) and +10 into XP--they're all pretty useful.

Thanks for the response guys!

I'll probably go the route of attack speed and crit chance for leveling up until 30 and we'll see how it goes from there.. I forget the skill at the moment but the basic attack that is kinda like chain lightning, might use that for multiple mobs.
Would I use the same artifacts/medal for that build?

ricochet blast is fun, but a pain against single target. I would probably use a MODOK medal then.