Quest: Do No Harm
Location: Sanctuary
Quest giver: Dr. Zed
This quest has you chop open his patient to get some eridium. After getting it the quest has you go to Tannis to talk to her. After talking to Tannis this quest can go into a stasis, to where it shows you've talked to Tannis, but won't let you progress. I believe this is caused by opening the vault in Roland's house before "officially" meeting Tannis.
Solution: If you get this bug QUIT WITHOUT SAVING IMMEDIATELY. Hopefully you didn't hit an autosave. The problem is Tannis has an intro, and something causes that intro to not happen. If it doesn't, you will get this bug.
I reloaded my last autosave. grabbed the quest "Do No Harm" got the eridium. WAIT UNTIL Dr. Zed is finished talking before going to see Tannis. Go into the house facing her and strafe for a moment, the intro should happen. Then talk to her and complete the quest, then continue with the quest to open Roland's Vault.
Hopefully this made sense, and works for everyone.