If the question is Pearsall vs. Coleman, I think I probably go Coleman since Pearsall's QB is out, and Kittle is on IR and Jauan is a gametime decision (I think?). Easy for the saints to stick McKinstry on him and shade with a safety and keep him under wraps.
Coleman will get his targets this week regardless if they put sauce on him or not, and I believe Aaron Glenn might consider putting Sauce on Shakir to take away Josh's crutch on scramble drills to limit big/explosive plays.
Hell, I'd consider starting Jeudy over the both of them this week if the Ravens defense is actually as bad as it looked last week. Flacco can clearly sling it still, and Jeudy is still Jeudy, and the Ravens should get out ahead to an early enough comfortable lead to make the Browns one dimensional and get away from the run that they'd like to establish in this game.