Players x command only affects the bosses no drop percentage (essentially thw chance to drop one more addituonal item of them).
This applies to both the regular and the the quest drop, but the chanes vary:
Andariel (quest):
at \players 1, nodrop = 19/41
at \players 3, nodrop = 6/28
at \players 5, nodrop = 2/24
at \players 7, nodrop = 1/23.
Andariel:
at \players 1, nodrop = 19/67
at \players 3, nodrop = 4/52
at \players 5, nodrop = 1/49
If you just melt andy go players 7, if you cant kill her in ~5 secs players 3 or 5 are solid options. If you need more than 15 secs, id just go p1.