People should not get their hopes up to much

Hunting for runes above IST is pretty much a waste of time imo. Ive played the game for 2-3 years and only seen 1 HR in LO from the blue guy in cold plains hell.
Not that I want to run into the time vs buying diccussion, cause for me its all about playing the game. I realy dont care what drops, but this information is good to have when you decide on hunting spesific areas.
Places like cows and travi also yield a fare amount of charms, and blue stuff that can be goodies.
Running countess and cubeing her and forge runes are my favorite way of getting HRs in game, Countess will also give you keys, wich also works as a currency.
The chest behind Meph have also yielded som mid-upper runes, not sure if it has specialy drop chances though.