Maybe yes, but there could be some variation.

Just like entering the Sands, and not finding Uber-Duriel just near the tp, in the center. This happens sometimes, and you have to teleport all over the map to find her...

it's always true, but the level can make 3 rights to produce a left, so it can vary as you say.

True, but smiter can easily maintain 75fcr on swap so teleporting doesn't suppose to be that painful.

It seems to be about doing stupid stuff as:
- putting spare points into vigor to rush through the town
- no fade/salvation, so res from inv enough to survive (eventually swapping treachery vs duriel to get fade while killing him)
- mercenary to help getting organs (slot for secondary armor)

Haven't tested yet if those below could have any sense:
- putting as much into str as it's possible to survive
- swapping enigma into forty while killing bosses
- maybe maintaining max as vs uber duriel

This post was edited by ischiLLy on Nov 20 2019 07:53pm

Build I used was

Kira Lo'd
Nigma
High lords
Ik gloves and belt
Exile
Last wish (for fade)
Gores
Fcr rings with res (48 fcr on switch)
Bunch of light res scs

What I would use now:

Guilly face umd
Highlords
Nigma
Grief
Gores
Crafted cb gloves with ias and lr
Arachs
Raven
Wisp
Exile
Bunch of all res scs and some lr scs, really only need stacked light res, lots of people don't know that

If we're talking about world record, I would definetely go with some full rejuvs, Gavel of Pain on switch, and of course without Life tap.