Always wanted to try, never have so i decided to give it a shot. Killing every single monster in a single game.
Ill post what drops i find from each act.

Act 1:

Trangs gloves
Nats Helm
Stormshield
Twitchthroe
5os flail
Lum rune

About to start act 2

Good luck ! and already good drops from act 1.
Don't forget to open all barrils, some monsters may hide into.

ooo good call, i may have to go back to act 1 and double check lol

Found a decent pair of gloves in arcane.

2passive/10ias/14dex
other then that so far just wiz spike and trangs belt

Act 2 complete.

what i found in act 2

trangs belt
wiz spike
nagel
hkey
3/16 sc
2passive/10ias/14 dex gloves

what character are you running

hdin

Act 3 complete. Found nothing worth keeping

Act 4 Complete. only drop was a 3/3 light facet

Im Now At frozen river, has taken forever to get this far lol, been at it for like 10 hours (with breaks) but remained in same game!

no a5 drops yet either, been a rough last few acts lol