Just like going to a higher tier map.
If you constantly die you switch back to lower tier maps.
Going deeper adjust the radius settings, monster life, monster strength and everything else that could be adjusted.
It is just D3 rifting they didn't invent something new
And proberly why they called it infinite depths

(without an end).
Edit: So to answer youre question: just play and go deeper whenever it is possible
This post was edited by caitlin on Sep 4 2018 12:11pm