The VS-120s only have a single set of speaker wire plugs, so you can only run one set from the amp to each speaker (you can't bi-amp these). However, the VS-120 has internal crossovers, to send the low frequencies to the sub, and the mids and highs to the other drivers. As such, you don't need to use the crossover function of the amp (and it really wouldn't work, since you can't run separate wires to the woofers and tweeters, anyway). Run the amp in standard Stereo Bypass mode, with one speaker connected to each speaker channel. The speakers are 4-Ohm speakers, and the amp is rated to be stable at 2 Ohms, so you're good there. Note: The VS-120 is rated for 250W max, and that Crown amp will put out 775W at 4-Ohms in a stereo configuration. So you'll want to be careful to not blow those speakers. If you check the manual for the amp, there should be a feature Crown calls Peak-x, which is designed to set the amp at levels which will prevent speaker clipping.