One of my favorite songs period. I am not religious, and barely noticed the religious underpinnings until I was looking at the lyrics. Not sure if this is correct as I do not know the story myself, but others discussing the lyrics indicated that it was about "Paul's conversion on the road to Damascus." I know nothing about that, but perhaps it has more meaning to some of you in here.
Regardless, it's one of my favorite songs, period. I just find it aesthetically beautiful, and Sufjan is a goshdamn genius.