tldr
they lowered the age for their hormone therapy studies from 13 to 8
they were giving destructive and irreversible gender transition to 8 year olds
then they upped the dosages to experimental values
2 out of 315 of the study already committed suicide while it was ongoing, let alone the years after
It wasn't just a cohort study on existing populations, since the same clinics were administering the drugs as carrying out the study
Here's the real kicker. The authors of the study claim the study shows hormone therapy improved psychosocial functioning among the teens. That was their conclusion;
https://www.nejm.org/doi/full/10.1056/NEJMoa2206297Quote
In this 2-year study involving transgender and nonbinary youth, GAH improved appearance congruence and psychosocial functioning. (Funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development.)
Well not for the ones who fucking killed themselves.
Here's some math, courtesy of me
The mortality rate for 12-20 year olds in america is 0.000696 per year average, with less than 25% from suicide (i dont care to multiply out the whole tables, its closer to 20%, lets say 25% for simplicity)
In a 2 year study with 315 participants, you'd have an expected value of ~0.11 suicides
With hormone therapy, their sample had 2 suicides. How many more killed themselves after the study ended?
Looks like a 2000%+ improvement in making their appearance congruent with a corpse