Quote (dro94 @ Oct 16 2020 12:30pm)
^Bazi
I've read the mortality rate of those being admitted to hospital has reduced from 30% during March/April to 14% now. Can you summarise the reasons why the mortality rate has halved?
I know that we're using Dexamethasone when patients need oxygen but I've also heard mention of a more 'holistic approach' that has helped to save lives in contrast to the focus on the lungs earlier on in the pandemic.
Quote (Thor123422 @ Oct 16 2020 12:32pm)
New disease needs time to figure out how to actually treat critical patients with it.
Doctors see it more -> Doctors get experience treating it -> Death rate goes down
Seasonal variability in vitamin D levels rises in the summer:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512566/Quote
Repeated serum samples were collected from the thrombocyte donors to study the intra-individual variations in S-25(OH)D. S-25(OH)D varied greatly over the year correlating with the intensity of the UV-B irradiation (rS = 0.326; p < 0.001). During January–March, a S-25(OH)D level below the thresholds of 50 and 75 nmol/L was observed in 58 and 88 %, respectively, and during July–September in 11 and 50 % (p < 0.001). S-25(OH)D was negatively correlated with body mass index and S-iPTH, but was significantly higher in holiday makers in sunny destinations, sunbed users, non-smokers, and in the physically active. The intra-individual analyses showed a mean increase in S-25(OH)D by 8 nmol/L/month between April and August.
This study states that there is a 54% increase in Covid19 infections amongst people with vitamin D levels that fall below 20ng/ml (deficient):
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0239252Quote
These results demonstrate an inverse relationship between circulating 25(OH)D levels and SARS-CoV-2 positivity. For the entire population those who had a circulating level of 25(OH)D <20 ng/mL had a 54% higher positivity rate compared to those who had a blood level of 30–34 ng/mL. The risk of SARS-CoV-2 positivity continued to decline until the serum levels reached 55 ng/mL. This finding is not surprising, given the established inverse relationship between risk of respiratory viral pathogens, including influenza, and 25(OH)D levels [14–16]. Vitamin D supplementation may reduce acute respiratory infections, especially in people with vitamin D deficiency [17]. A previous study found that each 4 ng/mL increase in circulating 25(OH)D levels was associated with a 7% decreased risk of seasonal infection, a decrement of approximately 1.75% per ng/mL [18]. This is remarkably similar to the 1.6% lower risk of SARS-CoV-2 positivity per ng/mL found in our adjusted multivariable model.
That's my story and I'm sticking to it.