its not our thread..............
why dont you give me a source were mRNA isnt genetics
A thread is not just page 1-53, it is a string of posts and comments regarding one subject.
#529 That is a fine way of saying "doing your own research" is equal to asking your neighbour via facebook.
Anyway, your source where mRNA does not reach the definition of DNA, it is the textbook used in biomedical sciences at the University of Leuven, Belgium, and presumably some others, during the first year of any biomedical major.
Becker's World of the Cell, Global Edition Paperback – International Edition, 3 July 2017
In any case, you have clarified what you meant if I am OK with foreign genetics being brought into our cells now, and so I can answer your question. If I interpret it correctly, you have a problem with mRNA being brought into our cells, because you consider mRNA to be foreign genetic material.
The short answer is simple. Genetics generally refers to DNA (the genome), which is the heritable material. mRNA does not reach this definition.
It is of important note that mRNA requires transporters to get inside of our cell nucleus, which nearly all cell lines in our body have (RBC's dump their nucleus and genetic material to carry a higher load of Hb, at the expense of being short-lived). Without such transporters, or rather, a "flag" (NLS or nucleus localisation signal) on the mRNA that tells the pre-existing transporters to let the molecule cross the border, there is 0% chance for it to reach our DNA unless in laboratory circumstances (electroporation). Even if it were able to enter the nucleus, it requires a reverse transcriptase to enter our genetics. This requires a "flag" that allows transcriptase to read it as something that needs to be integrated. An engineered mRNA obviously does not have this unless intended. It would also require further modification to be able to integrate into the DNA chain. I am not a 100% on this, but I don't think we have reached that level of engineering yet.
This post was edited by Leeevee on May 6 2025 02:10am