David Reimer

and 2) the entire body of literature on the endocrine system and pediatrics

David Reimer's life never intersected with puberty blockers, as he never took/was given them. I think you're conflating a few things.

Wrong, as usual. Lol. Comparing some old drug from 10+ years ago. Nice attempt, but clearly a fail.

Puberty blockers do not cause permanent changes to the body. And you can stop taking them at any time. If you decide to stop taking puberty blockers and did not take hormone therapy, your body will go back to the puberty that had already started.

https://www.stlouischildrens.org/conditions-treatments/transgender-center/puberty-blockers
Are Puberty Blockers Permanent?
No, puberty blockers are temporary:

Injectable blockers (such as Lupron) can last one, three or six months. Patients can continue getting injections until they decide what to do next.
Implants (such Supprelin), which are placed just under the skin in the arm, can last 12 to 24 months before they need to be replaced.

This post was edited by said_aouita on Oct 3 2023 03:17pm

You're pretty terrible at reading comprehension

/e anytime? So you can take them until you're 30, then you'll experience puberty just as normal in adulthood? Give me a break

This post was edited by El1te on Oct 3 2023 03:19pm

And you refuse to accept facts. Clearly you are a trump fan

I do undestand it, which is why I know you're making much ado about nothing. The hormones will continue production after you stop and can be supplemented if required with exogenous hormones or stimulating hormones to increase natural production.

The long term risks of these drugs are fairly well understood and you are blowing them massively out of proportion.

I am a biochemist after all.

It actually is how it works. We know that's how it works because lots of people go through puberty significantly earlier or later than others. Doctors aren't going to let you stay on them until you are 30, so the idea that you will go so extremely far out that it causes severe and irreversable damage is ridiculous.

when it says "are puberty blockers permanent?" it does not mean "is delaying your puberty for an extended period of time going to have the same outcome as a natural puberty?"

what it's clearly saying is "does taking puberty blockers one time permanently stop someone from experiencing puberty?" which isn't the argument precisely

people are arguing what negative effect the pause can have

I wouldn't say they're arguing it, as much as just blindly asserting severe permanent effects without and in spite of evidence.

nobody in this thread has directly cited a single reputable study to be fair