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Feb 2 2022 12:34pm
Quote (ofthevoid @ Feb 2 2022 12:26pm)
If all of the research and science community was on one side of this, it's a slam dunk but when several scientific sources are saying that Iverectmin does have some effect, why wouldn't I dig in my heels?

Also was looking at some of the other names that are pulling their music and my idea immediate thought is who are these people, literally never heard their names. I can see at least some of these nobodies pulling this as a publicity stunt. Kind of like slapping the parental advisory sticker to differentiate yourself back in the day. Should i hold my breath that someone relevant will pull their music?


Because you don't give equal credence to the absolute volumes of evidence that don't support your predisposition. You're basically taking this Japanese pre-clinical study and trying to use it as a bludgeon to discredit properly-vetted evidence to the contrary.

And your hypocritical attitude about "bUt mUh aPpEaL tO aUtHoRiTy" makes you look anti-intellectual, at best. You'll appeal to Kowa's "authority", but not Sioux's.
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Feb 2 2022 12:41pm
Quote (Surfpunk @ Feb 2 2022 01:34pm)
Because you don't give equal credence to the absolute volumes of evidence that don't support your predisposition. You're basically taking this Japanese pre-clinical study and trying to use it as a bludgeon to discredit properly-vetted evidence to the contrary.

And your hypocritical attitude about "bUt mUh aPpEaL tO aUtHoRiTy" makes you look anti-intellectual, at best. You'll appeal to Kowa's "authority", but not Sioux's.


That's one of the sources i pointed to, then there are others that i linked, which literally took 10 seconds of google digging. This is from a study that took place some time in August. Sioux simply dismissed it. Yes i take them as more authority over some random person on a 20 year old video game forum, as you should.


Quote
Therapeutic Advances:
Meta-analysis of 15 trials found that ivermectin reduced risk of death compared with no ivermectin (average risk ratio 0.38, 95% confidence interval 0.19–0.73; n = 2438; I2 = 49%; moderate-certainty evidence). This result was confirmed in a trial sequential analysis using the same DerSimonian–Laird method that underpinned the unadjusted analysis. This was also robust against a trial sequential analysis using the Biggerstaff–Tweedie method. Low-certainty evidence found that ivermectin prophylaxis reduced COVID-19 infection by an average 86% (95% confidence interval 79%–91%). Secondary outcomes provided less certain evidence. Low-certainty evidence suggested that there may be no benefit with ivermectin for “need for mechanical ventilation,” whereas effect estimates for “improvement” and “deterioration” clearly favored ivermectin use. Severe adverse events were rare among treatment trials and evidence of no difference was assessed as low certainty. Evidence on other secondary outcomes was very low certainty.

Conclusions:
Moderate-certainty evidence finds that large reductions in COVID-19 deaths are possible using ivermectin. Using ivermectin early in the clinical course may reduce numbers progressing to severe disease. The apparent safety and low cost suggest that ivermectin is likely to have a significant impact on the SARS-CoV-2 pandemic globally.


Edit: I also think scientific claims that are made much more recently hold higher significance. The study he linked was published in like June-July if i'm remembering correctly. The Japanese news is literally days old. I find it highly improbable that this more recent research happened in a vacuum and somehow they completely missed previous findings and analysis lol.

This post was edited by ofthevoid on Feb 2 2022 12:47pm
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Feb 2 2022 12:45pm
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Feb 2 2022 01:03pm
Quote (excellence @ Feb 2 2022 05:27am)
that user is a bernout who cleans petri dishes at a taxpayer-funded facility which is nothing more than a glorified 5th grade science lab

not that there’s anything wrong with said profession, so long as one isn’t filled with unwarranted self-importance like that user

despite all that faux bragging, it is way too smalltime for Moderna or Pfizer or even Dr Doolittle


lol

Quote (ofthevoid @ Feb 2 2022 10:41am)
That's one of the sources i pointed to, then there are others that i linked, which literally took 10 seconds of google digging. This is from a study that took place some time in August. Sioux simply dismissed it. Yes i take them as more authority over some random person on a 20 year old video game forum, as you should.

Edit: I also think scientific claims that are made much more recently hold higher significance. The study he linked was published in like June-July if i'm remembering correctly. The Japanese news is literally days old. I find it highly improbable that this more recent research happened in a vacuum and somehow they completely missed previous findings and analysis lol.


Again, the Japanese research group didn't actually publish any data. They just said in their non-clinical assay it showed an effect. Without seeing the underlying data its a meaningless claim from a company trying to boost its own share price on hype.

To really hammer the point home, almost every trial testing ivermectin to date has had major methodological concerns, or outright evidence of fraud (Copy-pasted rows of patient data, statistically impossible results, calculation errors). There's a major trial in Brazil looking at repurposing drugs that is of quite high quality (The together trial) that's already identified an old compound as effective against Covid (Fluvoxamine) that's tested and ruled out Ivermectin and hydroxychloroquine. Since they're testing a panel of old off patent drugs and have identified hits that show improvement, its hard to argue they're in the pocket of big pharma trying to suppress the evidence. You should check it out, its really high quality science. https://www.togethertrial.com/trial-specifications

This post was edited by Sioux on Feb 2 2022 01:10pm
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Feb 2 2022 01:08pm
in b4 neil young is a pedo
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Feb 2 2022 01:14pm
I find it hilarious that the same people who REEEE about following the money with regard to Blackstone and Neil Young will completely ignore the massive financial intertwining between Blackstone (and it's CEO Stephen Schwarzman) and Donald Trump, Jared Kushner and Kushner Companies, the House of Saud, and others.

Follow THAT money, why don't you?
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Feb 2 2022 02:50pm
Quote (CyrusTheGreat @ 29 Jan 2022 00:30)
In all fairness, he has the same right to choice as the rest of us. He made a choice and moved forward with.

Now, if there becomes a media tour about all of his lost profits, then, that changes things. If he's willing to accept the ramifications of his decisions, that's fine, but, when you choose to do something, there won't be any public sympathy because it ended up being negative for you.


I agree with your argument that he has the right to choose what to do with his property.

But I think theres a diffrence saying "I don't like the some of the context on spotify, so I am removing my songs".
And saying " remove this or I will remove my songs".

One is morally right and one isn't.

This post was edited by Tapir on Feb 2 2022 02:51pm
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Feb 2 2022 03:16pm
Quote (JohnnyMcCoy @ Feb 2 2022 10:45am)


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Feb 2 2022 04:31pm
Quote (Surfpunk @ Feb 2 2022 02:14pm)
I find it hilarious that the same people who REEEE about following the money with regard to Blackstone and Neil Young will completely ignore the massive financial intertwining between Blackstone (and it's CEO Stephen Schwarzman) and Donald Trump, Jared Kushner and Kushner Companies, the House of Saud, and others.

Follow THAT money, why don't you?


Because they're fucking liars.
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Feb 2 2022 11:50pm
Joe Rogan brings up some valid points. Discussion into the origins of the disease (i.e. entirely zoonotic or a lab release) was banned as recently as a year or so ago. Masks were ineffective until they were effective and now cloth masks are maybe not effective again. The vaccine absolutely prevented transmission until it didn't.

Zero-covid policies have been an abject failure. Lockdowns have failed to contain the virus and carried enormous social and health costs. School lockdowns have successfully destroyed millions of years of education, and will be major drivers of poverty, income inequality, and shortened lives for years to come. Censoring the debate on Covid has failed as policy. The truth can only be ascertained with rigorous and unconstrained public debate.
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