What is the "settled data"? I'm only passively aware of Red Dye #3 studies being linked to thyroid cancers in male rodents, where the rodents were exposed to significantly higher amounts than even in human consumption, and that the rat thyroid/hormone/iodine uptake system is meaningfully different in physiology so as to question whether it is applicable then to humans.
https://oehha.ca.gov/sites/default/files/media/downloads/risk-assessment/report/healthefftsassess041621.pdfthe underlying study that i thought had the best methodology:
Quote
Two more recent studies addressed many limitations of earlier study designs. Bateman
et al. (2004) included 277 three-year-old children in England and was a randomized,
cross-over, double blinded, mixture study that included both children with and without
identified hyperactivity and used several validated outcome measures. Based on parent
scores, a statistically significant increase in hyperactivity was seen with the dye
challenge compared with placebo. The second study conducted by the same research
group using a similar design (McCann et al. 2007) enrolled 153 three-year-olds and 144
eight- and nine-year-old children. Validated outcome measures were combined to
create standardized weekly global hyperactivity aggregate (GHA) scores. Statistically
significant adverse effects were demonstrated for all three-year-old children, effect size
0.20 (95% C.I. 0.01-0.39) and was greater for those who consumed at least 85% of the
juice containing the dye dose and had no missing data (effect size 0.32; 95% C.I. 0.05
– 0.60). Statistically significant effects were also seen in eight and nine year olds who consumed at least 85% of the juice. A subsequent study (Stevenson et al., 2010) using
the same cohort found evidence of moderation by gene polymorphisms in histamine
degradation and the dopamine transporter gene. The effect sizes seen in these studies
are similar to the overall effect size identified in high-quality studies evaluated in the
meta-analysis by Nigg et al. (2012), 0.22 (95% C.I.; 0.01 – 0.41). Examination of
psychometric tests of attention specifically, an objective and relevant metric, yielded a
higher effect size, 0.27 (p= 0.007). When limiting the analysis to studies that only
included FDA dyes, the effect was 0.34 (p= 0.017). The effect size was not different
between studies that selected participants based on attentional problems/ADHD status
and those that used a general population indicating that the general childhood
population, not just those with diagnosed ADHD, is at risk for the impacts of food dyes
on behavior.
cancer was ruled out as a risk in humans, but not animals. however neurological issues in children seems to be fairly well observed among a wide array of studies.
Many of the food dyes are poison.
Red 40 is notorious for negative side effects.
I hope RFK actually succeeds on this.
This, Fluoride was sold as rat poison.
It's a by product of the aluminum industry, among other industry.
It's cheaper to feed the public Fluoride in tap water than it is to dispose of it properly.
Dentists are encouraged to push Fluoride by lobbyists.
Your mouth produces a natural chemical to keep your teeth strong.
there's nothing wrong with fluoride to treat teeth, it just shouldn't be consumed.
This post was edited by thesnipa on Jan 15 2025 03:18pm