I haven't played around with it much, but so far, I haven't had very much luck jackpotting. I usually spend 4-6 hours grinding in skirmish before I try picking an item (no boxes from what I've heard) and seeing what I get. So far I haven't been very successful and usually break even or lose out on the total of what I jackpot. Was hoping someone would have some tips here =)

Jackpotting crystals is usually the best method.

This is pre voo buff and havent run it since as there might be better loot in there now as its tunned to your level. You can take any item crystal or high ish mat 200k in first slot. Run voo get almost all boxes in other slots. Main ones you want is Divine, Freezing and Conq then just keep jackpot running for as long as possible.

Longer you build jackpot the better results, i normally give up around 1 Billion mark worth of items in jackpot then doing it.

Our guild leader did one for about 7-8 billion so he could jackpot a book hehe.